This type of Addison’s is called autoimmune Addison’s.Ĭauses Addison's can also be caused by an infections (such as tuberculosis or HIV) damaging the adrenal glands. This occurs when body’s immune system making a mistake and attacking and destroying the cells of the adrenal glands in error. Primary adrenal insufficiency or primary Addison's disease autoimmunity is the most common cause of Addison’s disease. People with Addison's disease develop symptoms as a result of this loss of adrenal hormones. This means that the adrenal gland cannot produce the hormones glucocorticoids (especially cortisol), mineralocorticoids (especially aldosterone) and sex steroids. Adrenal androgens control some body hair growth in women but have little importance in men.Īddison's disease is caused by the destruction of the cortex of each adrenal gland. ![]() Aldosterone is essential to keeping a normal level of salt and water in the bloodstream to maintain blood pressure. It is released by the adrenal glands throughout the day but its production increases in times of illness or injury.
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